A new form of mesotherapy and entry of active substances without needles.
- Mesoporation is a complex process that allows mesotherapy in the tissue at a depth equivalent to mesotherapeutic injection.
- The duration of treatment is 10 - 20 minutes, depending on the area of treatment (for the face and neck treatment lasts 15 minutes and cellulite treatment about 30 minutes)
- The depth of penetration ranges from very superficial, 2-3mm, to several cm
- Mesoporation is new, needle-free injection treatment, different from Iontoforese. This treatment brings 99% of the mesotherapeutic formula in a depth of 1 cm and 65% of the formula to a depth of 6 cm. Unlike traditional Iontoforese that brings only 10% of the product (ionic solution) at a depth of 1 cm.
Mezoporation is a new and unique method, developed exclusively for mesotherapeutic treatments, based on four modalities:
3. Mechanical pressure
4. pH gradient
is the process of cellular membrane reorganization, as a result of electrical impulses from an active electrode. The pulses form a temporary channels, mesopore, in a cellular membrane through which the molecules of active substance penetrating. The process is possible due to the specific behavior of fatty acids that are an integral part of the epidermis and other tissues.
The epidermis contains multiple layers of lipids. Under the influence of specific el. Impulse lipid layer can be reorganized and will open the new channels on stratuum corneum. The process covers non-polar ends of fatty acids. Water and non-water solutions with active ingredients entering into deep skin tissue trough these channels .
Mesopores "last" for 15-20 seconds or even up to a few minutes. Size of the mesopores is from 40 to 250 microns.
Positively charged active substance particle been repulsed by positively charged electrode in the tissue through the mesopores. The most commonly used solutions are mesotherapy "+" positively charged solutions.
In the case of negatively charged active substances, the polarity of the electrodes can be replaced.
The therapist produces mechanical pressure with electrode. This pressure "pushing" the solution through mesopores , into the skin tissue.
The isoelectric point of the skin is -4. Under physiological conditions, the surface of the skin soaked active ingredient to 7.4 (or ~), electro favors the "+" positively charged molecules.
"-" negatively charged solutions are also not the problem. Mosoporation is possible with any kind of mesotherapy solution as long as they are mixed with right carrier.
Mesoporation device is important for the transport of substances into the tissue without needles. It is used for rejuvenation, wrinkles, fat, cellulite, skin whitening, acne and other skin defects. It stimulates production of collagen and elastin, tightens tissue and also the infuse the active substances. It is aslo a good treatment before and after surgical intervention.
Mesoporation provides effective introduction of formulation, depending on the desired effect.